Dieter Schinzer

Prof. Dr. rer. nat. habil. Dieter Schinzer
Lehrstuhl Organische Chemie
CURRICULUM VITAE | |
Name: Dieter Schinzer | |
Date and Place of Birth: | |
July 7, 1953, Gudensberg (Germany) | |
Nationality: | |
German | |
Education (Degrees, Dates, Universities): | |
Undergraduate school, Department of Chemistry, University of Marburg (1974-1977). Graduate school, Department of Chemistry, University of Bonn (1977-1980). PhD with Prof.M.T.Reetz in 1980. | |
Habilitation with Prof.E.Winterfeldt in 1986 | at the University of Hannover. |
Career/Employment (Employers, Positions and Dates): | |
Feodor-Lynen fellow (Alexander v. Humboldt-foundation), Department of Chemistry, University of California, Berkeley, USA with Prof.C.H.Heathcock (1980-1982). Liebig-fellow (Fonds der Chemischen Industrie), Department of Chemistry, University of Hannover with Prof.E.Winterfeldt (1983-1986). Heisenberg-fellow (Deutsche Forschungsgemeinschaft, DFG), Department of Chemistry, University of Hannover (1986-1989). Professor of Chemistry on a temporary position at the Department of Chemistry, University of Göttingen (Schöllkopf chair) (1989-1990). Visiting Professor of Chemistry at the Department of Chemistry, University of Wisconsin, Madison, USA (1990). Associate Professor of Chemistry, Department of Chemistry, University of Braunschweig (1990-1996). Full Professor of Chemistry, Department of Chemistry, University of Magdeburg (1997-present). Offer: Chair for Synthetic Organic Chemistry, University of Oslo, Norway (April 2001). | |
Founder, Consultant and Chief Scientific Officer (CSO) of MOLISA (Molecular Links Sachsen-Anhalt) GmbH, Magdeburg (2002-present). | |
Dean of the Faculty of Chemical Engineering (2002-2005). | |
Consultant with several Pharmaceutical Companies. | |
Research: | |
Organometallic chemistry (silicon-, tin-, and manganese chemistry), developement of new synthetic methods and application to the total synthesis of bioactive natural products, drug design by structure-activitiy-relations (SAR), molecular modeling, and computer applications in chemistry. | |
Honours, Awards, Membership of Professional Societies: | |
GDCh (Gesellschaft Deutscher Chemiker), ACS (American Chemical Society), ECS (European Chemical Society). Werner von Siemens-medal (1986); young scientist award (Dozentenstipendium, Fonds der Chemischen Industrie, 1988); NATO award (1988) for the organization of an international conference about "Selectivities in Lewis Acid-Promoted Reactions" in Athens, Greece. | |
International Activities: | |
COST (European Cooperation in the Field of Scientific and Technical Research) Managment Committee Member for Actions D12 (Chairman 1998; OrganicTransformations: Selective Processes, Asymmetric Catalysis, and Enzymes), D24 (Sustainable Chemical Processes: Stereoselective Transition Metal Catalysed Reactions), and Action Proposer and Chairman (2002-2006) for D 28 (Natural Products as a Source for Discovery, Synthesis, and Application of New Pharmaceuticals). German Member of the Techical Committee of COST Chemistry (2000-2006).; Liaison Member of the Technical Committees of COST Medicine and Health, and Biotechnology and Food (2002-2006). German Member and Chairman (2006-2009) of the new Domaine Committee of COST "Chemistry and Molecular Sciences and Technologies" |
- Organische Chemie,
- Natur- und Wirkstoffsynthese,
- Medizinische Chemie,
- Struktur-Aktivitättsbeziehungen
2019
Dissertation
Of proteins and lipids - a molecular dynamics study of membrane-bound Rab5
In: Magdeburg, 2019, XIX, 158 Seiten, Illustrationen, Diagramme, 30 cm ; [Literaturverzeichnis: Seite 111-122]
2014
Dissertation
Die Entwicklung nachhaltiger Synthesemethoden zur atomökonomischen Transformation von 1-Vinylpropargylalkoholen mit Übergangsmetallkomplexen redoxaktiver Liganden als Katalysatoren
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, III, 173 S., graph. Darst.
2012
Dissertation
Development of a glucose-oxygen enzymatic fuel cell
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2012, IX, 118 S., graph. Darst.
Progress towards the total synthesis of sorangicin
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2012, IX, 144 S., graph. Darst.
2010
Originalartikel in begutachteter internationaler Zeitschrift
(3R *,5'S *)-6,7-Dimethoxy-3-(4'-methoxy-6'- methyl-5',6',7',8'-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5'-yl)isobenzofuran-1(3H)-one (racemic α-noscapine)
In: Acta crystallographica / E - Chester: International Union of Crystallography, Bd. 66.2010, 3, S. o570, insges. 11 S.
2004
Buchbeitrag
The aldol reaction in natural product synthesis : the epothilone story.
In: Mahrwald, Rainer (Hrsg.): Modern aldol reactions. Vol. 1 : Enolates, biocatalysis and natural product synthesis. Weinheim : Wiley-VCH, 2004, S. 311 - 328
Originalartikel in begutachteter internationaler Zeitschrift
Studies toward the total synthesis of sorangicins : asymmetric synthesis of the key fragments.
In: Synlett : accounts and rapid communications in synthetic organic chemistry [Stuttgart](2004), Nr. 15, S. 2689 - 2692
Synthesis and biological evaluation of furano-epothilone C.
In: Synlett : accounts and rapid communications in synthetic organic chemistry [Stuttgart](2004), Nr. 8, S. 1375 - 1378
Synthesis of Furano-Epothilone D.
In: Chemistry : a European journal [Weinheim] 10(2004), Nr. 13, S. 3217 - 3224
2000
Originalartikel in begutachteter internationaler Zeitschrift
Intramolecular [3+2]-hetero-annulation of allylsilanes with 1,3-cyclohexanedions and its application in the synthesis of hexacyclic hopane triterpenes.
In: Synlett : accounts and rapid communications in synthetic organic chemistry [Stuttgart](2000), Nr. 9, S. 1265 - 1268
Synthesis and biological evaluation of aza-epothilones.
In: ChemBioChem : a European journal of chemical biology [Weinheim] 1(2000), Nr. 1, S. 67 - 70
Originalartikel in begutachteter nationaler Zeitschrift
Epothilone : neue Wirkstoffe gegen Krebs.
In: Magdeburger Wissenschaftsjournal [Magdeburg] 5(2000), Nr. 1, S. 23 - 30
Abgeschlossene Projekte
- Sorangicine und Neosorangicine als neue Strukturtypen für Breitbandantibiotika
Laufzeit: 01.06.2018 - 31.05.2021 - Synthese von neuen Antitumorwirkstoffen
Laufzeit: 01.09.2017 - 31.10.2018 - Neue Breitbandantibiotika aus Myxobakterien
Laufzeit: 01.05.2017 - 30.04.2018 - Totalsynthese von Sorangicin A
Laufzeit: 01.05.2007 - 30.06.2010 - Total Synthese von 8,9-Dehydro-epothilon C
Laufzeit: 01.05.2006 - 30.03.2010 - Totalsynthese von Sorangicin - Synthese der Trieneinheit und Verknüpfung der Substrukturen
Laufzeit: 01.04.2006 - 31.03.2009 - Neue hochwertige pflanzliche Inhaltsstoffe" Teilprojekt Untersuchungen zur Charakterisiering pflanzlicher Inhaltsstoffe aus Pflanzen der Gattung Allium
Laufzeit: 01.04.2005 - 31.03.2008 - Synthese von Epothilon-Analoga
Laufzeit: 01.01.2006 - 31.12.2007 - Totalsynthese von Sorangicin - Aufbau des Dihydropyransystems
Laufzeit: 01.01.2006 - 31.12.2006 - Bindungsstudien mit Epothilonen
Laufzeit: 01.01.1999 - 31.12.2000 - Synthese von Epothilon-Analoga
Laufzeit: 01.01.1997 - 31.12.1999 - Totalsynthese von Hopan-Triterpenen
Laufzeit: 01.01.1998 - 31.12.1999
- Helmholtzzentrum für Infektionsforschung Braunschweig und AnalytiCon Discovery GmbH Potsdam
- Chemistry ( Link zur LV im LSF )
- Modern organic synthesis ( Link zur LV im LSF )
- Organische Chemie ( Link zur LV im LSF )